產(chǎn)品名稱：

活性氧Ligustrazine (hydrochloride)，CAS No. 76494-51-4

產(chǎn)地：西安

規(guī)格：1mg 5mg 10mg

純度：99%

用途：僅用于科研

狀態(tài)：固體/粉末

儲藏條件：冷藏-20℃

溫馨提示：僅用于科研，不能用于人體實驗！

說明：提供使用說明，核磁圖譜，包裝，價格，產(chǎn)地，制備方法，應用，穩(wěn)定性，溶解度，簡單合成等各種信息　　

Ligustrazine is a compound that has been found in L. wallichii and has diverse biological activities, including antioxidant, anti-inflammatory, neuroprotective, and anticancer properties.1,2,3 It inhibits hydrogen peroxide-induced decreases in cell viability and the levels of superoxide dismutase (SOD) and glutathione peroxidase (GPX) and increases in reactive oxygen species (ROS) and malondialdehyde (MDA) levels in human umbilical vein endothelial cells (HUVECs) when used at concentrations of 100 and 150 μg/ml.1 Ligustrazine (50 and 100 μM) inhibits prostaglandin E2 (PGE2) production induced by LPS and IFN-γ in primary rat glia.2 It reduces infarct volume, cortical edema, and cortical PGE2 levels in a rat model of transient focal cerebral ischemia induced by common carotid artery and middle cerebral artery occlusion when administered at a dose of 20 mg/kg. Ligustrazine inhibits the proliferation of MG-63, Saos-2, and U2OS osteosarcoma cells (IC50s = 10.3, 24.7, and 54.7 mg/ml, respectively) in vitro and reduces tumor growth in an MG-63 mouse xenograft model when administered at a dose of 100 mg/kg every other day.

更多推薦：

活性氧Umbelliferone，CAS No. 93-35-6

活性氧Aucubin，CAS No. 479-98-1

活性氧Thioredoxin 2 Rabbit Monoclonal Antibody (Clone 001)，Mitochondrial Thioredoxin

活性氧p16INK4A (C-Term) Rabbit Monoclonal Antibody (Clone RM409)

活性氧Astilbin，CAS No. 29838-67-3

活性氧Palmitic Acid，CAS No. 57-10-3

活性氧2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine，CAS No. 105650-23-5

活性氧BCI (hydrochloride)，CAS No. 95130-23-7

活性氧MAVS Monoclonal Antibody (Clone 7B9)，CARD Adapter-Inducing Interferon-β

活性氧Helicobacter pylori NAP Rabbit Monoclonal Antibody (Clone RM414)，H. pylori Neutrophil-activating Protein

活性氧β-Caryophyllene，CAS No. 87-44-5

活性氧IFN-γ (mouse, recombinant)，Type II Interferon，Interferon-γ

活性氧Maresin 1-d5 MaxSpec? Standard，7(R)-MaR1-d5，7(R)-Maresin 1-d5

活性氧Coenzyme Q2，CAS No. 606-06-4

活性氧p16INK4A (C-Term) Rabbit Monoclonal Antibody

活性氧Propiconazole-d3 (nitrate)，CAS No. 2699607-26-4

編輯：XAQYBIO HAO，2023年4月23日。